CRX coding variants are associated with at least three forms of inherited retinal disorders (IRDs) that cause blindness, including Leber congenital amaurosis 7 (LCA7, OMIM: 613829), Cone-rod dystrophy 2 (CoRD2, OMIM: 120970), retinitis pigmentosa (RP, OMIM: 268000). The gene discussed is CRX; the disease is blindness (disorder).