KCNQ1OT1 and myocardial infarction: In a study on MI mice, it was found that lncRNA KCNQ1OT1 mediated imprinted gene silencing by recruiting DNMT1 and elevating the CpGi methylation level in the promoter region of runt related transcription factor 3 (RUNX3), which in turn suppressed RUNX3 expression levels.