Previous research has shown that knockdown of KCNQ1OT1 can modulate adiponectin receptor 1 and attenuate ischemia-reperfusion (I/R) injury after acute myocardial infarction (AMI) by affecting the p38 MAPK/NF-κB signaling pathways (Li et al., 2017). This evidence concerns the gene KCNQ1OT1 and myocardial infarction.