Innovative treatments for HCC have been found as a result of the precise targeting of vital pathways, which include the receptor tyrosine kinase pathways, the Ras mitogen-activated protein kinase (Ras/Raf/MAPK), the phosphatidylinositol 3-kinase (PI3K)/ protein kinase B Akt/mammalian target of rapamycin (mTOR), the Wingless/Integrated (Wnt)/β-catenin signaling pathway, the ubiquitin/proteasome degradation pathway, and the hedgehog signaling pathway [5,6]. The gene discussed is MTOR; the disease is hepatocellular carcinoma.