Therefore, to determine whether or not ectopic IL24 would selectively terminate the melanoma cells used herein, PIKFYVE‐sensitive melanoma A375 and PIKFYVE‐insensitive human HFF1 and Hs27 foreskin fibroblasts [7] were infected with the same adenovirus (AdV) derived IL24 expression vectors used in previous studies. The gene discussed is IL24; the disease is melanoma.