By combining the circulating levels of tissue inhibitor of metalloproteinases‐1 (TIMP‐1)—which has been previously correlated with Ccx in patients—with cachexia‐associated liver parameters (C‐reactive protein, ferritin, albumin, total protein and gamma‐glutamyl transferase), the TIMP1/liver/cachexia (TLC) score shows promising potential to detect Ccx [125]. Here, ALB is linked to Cachexia.