KIT and gastrointestinal stromal tumor: Within the larger group of KIT-mutated GIST, different mutations’ hotspots have been reported, of which the vast majority of KIT mutations are found in exon 11 coding for JM (66–71%), exon 9 coding for extracellular domain (13%), exon 13 coding TK domain I (ATP binding pocket) (1–3%), and exon 17 coding for TK domain II (activation loop) (1–3%).