HLA-C and neoplasm: Except for TAMs enriched in PTs and MTs, the other types of macrophages were enriched in NTs, especially the Kupffer-derived macrophages (Mac_MARCO) and MHC+ macrophages (Mac_VSIR), and their signature scores had no impact on tumor patient outcomes (Fig. 5C, E and Additional file 1: Fig. S6A, B).