In the 8-CRLs studied, THAP9-AS1, CDKN2A-DT, GCC2-AS1, AL132800.1, STARD4 − AS1, and WDFY3-AS2 were reported to be biomarkers related with cuproptosis in HNSCC [18–23]. Here, WDFY3 is linked to head and neck squamous cell carcinoma.