The most common adverse events of any grade occurring in at least 25% of patients were mucositis (N = 39/57, 68.4%), asthenia (N = 27/57, 47.4%), decreased weight (N = 18/57, 31.6%), rash (N = 18/57, 31.6%), hypercholesterolemia (N = 16/57, 28.1%), hypertriglyceridemia (N = 15/57, 26.3%), alanine aminotransferase increased (N = 15/57, 26.3%) and dyspnea (N = 15/57, 26.3%). The gene discussed is GPT; the disease is Hypercholesterolemia.