To test the outcomes of cGAS activation in cancer cells, we transduced cGAS KO MA9 cells with an inducible cGAS-activating mutant (ΔN)45 or corresponding cGAS WT (Fig. 6k) and then implanted parental (cGAS KO), cGAS WT or ΔN-expressing cells into B6 mice to analyze leukemogenesis. Here, CGAS is linked to cancer.