Indeed, compared to WT parasite-infected mice, Tb927.6.4140-deficient parasite-infected mice exhibited reduced anemia as well as serum ALT (liver-specific injury marker) and AST (more general tissue injury marker) levels at day 6 p.i. (acute phase) and day 22 p.i. (chronic phase), suggesting a lower immunopathology (Fig. S6). This evidence concerns the gene GPT and anemia (phenotype).