Moreover, a multivariate Cox regression analysis revealed that the baseline ITGA1 level was independently associated with re-hospitalisation (HR 2.331 [95% CI 1.387, 3.917], p=0.001) after adjusting for age, duration of diabetes, smoking, atrial fibrillation history and baseline creatinine levels (Table 6). The gene discussed is ITGA1; the disease is diabetes mellitus.