CD8A and congenital rubella syndrome: On the contrary, a correlation between the number of CD8+ CAR-T cells and CRS severity has been observed in patients.55 This suggests that the toxicity observed in BALB/c mice may be specific to this murine strain and, although further investigation is required, that the liver phenotype and serum profiling in the 4T1-BALB/c model indicate an MAS-like event.