The results showed that ectopic expression of miR-200b targeted zinc finger E-box-binding homeobox 2 (ZEB2) and rendered SCLC sensitive to chemotherapeutic drugs such as cisplatin, adriamycin, and etoposide; furthermore, the expression of miR-200b was downregulated in resistant cells in comparison to the sensitive parental cells[169]. This evidence concerns the gene ZEB2 and small cell lung carcinoma.