Qiao et al[138] found that CAF-derived interleukin 6 (IL-6) conferred cisplatin resistance in esophageal squamous cell carcinoma (ESCC) by upregulating C-X-C motif chemokine receptor 7 (CXCR7) expression via STAT3/NF-κB pathways. The gene discussed is ACKR3; the disease is esophageal squamous cell carcinoma.