Qiao et al[138] found that CAF-derived interleukin 6 (IL-6) conferred cisplatin resistance in esophageal squamous cell carcinoma (ESCC) by upregulating C-X-C motif chemokine receptor 7 (CXCR7) expression via STAT3/NF-κB pathways. Here, STAT3 is linked to esophageal squamous cell carcinoma.