For further validation of the prognostic power of combined clinical features and SLC20A1 expression, ROC curve has been created and the AUC for survival rates at 1, 3, and 5 years were 0.676, 0.750 and 0.716, with moderate prediction accuracy (Figure 5C), indicating the significant ability of the developed monogram for predicting HNSCC prognosis. This evidence concerns the gene SLC20A1 and head and neck squamous cell carcinoma.