TNF and neoplasm: TCR135-T cell and rEBNA1-loaded DC coculture supernatant was sufficient to kill SNU-719-EBNA1 tumor cells without the need for cell-cell contact, as shown in Figure 7D. Interestingly, cytolysis of SNU-719-EBNA1 tumor cells by the coculturing supernatant was significantly inhibited when a TNF-α–neutralizing antibody was added (Figure 7D).