In Model 3, when the outcome variable was pleural effusion, compared with the lowest quartile (Q1), the highest quartile (Q4) of IL‐1β reflected an increased risk of pleural effusion (OR = 2.36, 95% CI = 1.21–4.58, p < .05), the third quartile (Q3) of IL‐6 reflected an increased risk of pleural effusion (OR = 4.67, 95% CI = 2.27–9.61, p < .001), the third quartile (Q3) of IL‐8 reflected an increased risk of pleural effusion (OR = 2.95, 95% CI = 1.51–5.79, p < .01), and the highest quartile (Q4) of IL‐10 reflected an increased risk of pleural effusion (OR = 3.20, 95% CI = 1.61–6.36, p < .01). Here, CXCL8 is linked to Pleural effusion.