It is highly conceivable that the regulatory effect of mmu-miR-10a-5p, mmu-miR-488-3p, and mmu-miR-1224-5p on anxiety-like behavior induced by fecal transplantation is implemented through Creb1-mediated signaling pathways such as AMPK, cAMP, and PI3K-Akt. Here, AKT1 is linked to Anxiety.