L1CAM and Alzheimer disease: At the same time, we observed multiple proteins in this group to be the protein-encoding marker genes for neurons (NRG1, a co-receptor for of RENL, a recent gene identified in AD resilience,86, NTRK2, L1CAM, and EPHA7) and astrocytes (CTNNB1, FGFR3, and PDGFC), with most of them being enriched in signaling related processes which suggest microglia neuron communication.