In accordance with these data, RNF34 mRNA overexpression was associated with unfavorable overall survival (OS), cancer-specific survival (CSS), and progression-free survival (PFS) in RCC as evaluated by Kaplan-Meier estimates and significant log-rank p-values (each log-rank p < 0.01; Figures 1E-1G). The gene discussed is RNF34; the disease is cancer.