These conditions include uterine fibroids exceeding 3 cm and/or numbering more than 3, as well as individuals with polyps, pelvic inflammatory disease, bleeding disorders, severe anemia (Hb < 7 gm%), chronic renal disease, uncontrolled thyroid dysfunction, liver disease, uncontrolled hypertension, and diabetes mellitus. The gene discussed is GSTM1; the disease is liver disorder.