Proteins that regulate glycolysis (PGK1, PGAM1, ENO1, PKM, TKT), ammonia detoxification (GLUD1), and other metabolic pathways (LDHA, GAPDH, MDH2) were reported to be differentially expressed in mouse xenograft colorectal tumor models with different radio- responsiveness (22). Here, PGAM1 is linked to colorectal neoplasm.