ITGA2B and Dilatation of the cerebral artery: Before the application of new platelet surface GP IIb/IIIa receptor antagonists such as tirofiban and abciximab in the endovascular therapy of intracranial aneurysms, a 3–5 day preoperative oral dual antiplatelet drug was often used to prevent perioperative TEs in patients with unruptured intracranial aneurysms.