lactis NJ241 (abbreviated as NJ241) increases intestinal GLP-1 expression and has a preventive effect on the occurrence of MPTP-induced PD, and whether this effect is mediated through the GLP-1R/PGC-1α signaling pathway, we intervened with NJ241 in the classic MPTP-induced PD mouse model. Here, PPARGC1A is linked to Parkinson disease.