BRAF and rectal neoplasm: When the analysis of mutations in the BRAF gene was restricted to the p.(Val600Glu) mutation, the mutation frequency differed between right-sided tumors and left-sided tumors (10.7% vs. 3.6%, p < 0.0074), whereas rectal tumors (0.5%) differed greatly in frequency from left-sided tumors (0.5% vs. 3.6%; but after Bonferroni correction not significant p < 0.0484) and significantly from right-sided tumors (0.5% vs. 10.7%; p < 0.0001).