Other examples of lncRNA dependencies observed in several cell lines are SNHG7 and SNHG5 (SNHGs with oncogenic function), CYTOR66,67 (involved in cell migration and cytoskeleton organization), PVT1 (ref. 68) (a MYC regulator, commonly overexpressed in cancer) or FTX69,70 (a XIST regulator involved in DNA methylation and X chromosome inactivation). The gene discussed is MYC; the disease is cancer.