CYP2C9 and adenoma: It has been reported that rs1057910 genotype of CYP2C9 was related to increased risk of adenoma recurrence (aRR = 1.47, 95% CI: 1.19–1.83) [39], or developing sporadic colorectal carcinoma (aOR = 2.77, 95% CI: 1.1653–4.643) [40].