CYP2C9 and adenoma: Meanwhile, several studies have observed that CYP2C9 rs1057910 polymorphism was associated with increased risk for adenoma recurrence (aRR = 1.47, 95% CI 1.19–1.83) [39], or developing sporadic colorectal carcinoma (aOR = 2.589, 95% CI: 1.549–4.330) [40].