CD4 and COVID-19: In contrast to these findings, previous studies in PWOH found heightened immune activation and exhaustion in those hospitalized for acute COVID-19.6,26–34 We also performed correlations between CD4% and our immune data to determine whether CD4% (13%–45%) influenced our findings and observed no significant relationships (see Table, Supplemental Digital Content 9, http://links.lww.com/QAI/C243, CD4% correlations), with the only exception a negative correlation with nonclassical monocytes (P = 0.030).