However, in line with the transcriptional profiling data, when, we measured the levels of sIL-7Rα (CD127) in plasma we found that patients infected with L. donovani, both active infection (D-0) and 30 days post treatment (D-30) had significantly lower levels of sIL-7Rα compared to ECs (p<0.0001) (Fig 1C). This evidence concerns the gene IL7R and infection.