CD163 and neoplasm: However, the number of CD163+ TAMs differed significantly between spatial compartments (q = 3.5 × 10−9; Benjamini–Hochberg corrected Mann–Whitney U test; Fig. 1B) with a 5.3-fold higher median count in the peritumoral stroma (5.16 ± 4.29) compared with the tumor islets (0.97 ± 0.76).