In the present study, we performed single-cell RNA sequencing (scRNA-seq) analysis of 11 tumor tissues and 5 adjacent normal adrenal medullary tissues from 4 sporadic PCC patients with unclassified mutations and 1 hereditary PCC patient with Von Hippel-Lindau (VHL) syndrome caused by germline mutation in VHL. Here, VHL is linked to adrenal gland pheochromocytoma.