NUCB2 and diabetes mellitus: There was a strong negative correlation between serum nesfatin-1 level and HOMA-IR and a moderate positive correlation between serum nesfatin-1 level and eGFR and HDL cholesterol, while serum nesfatin-1 level had a moderate negative correlation with the duration of diabetes, waist circumference, TC, TG, serum creatinine, serum urea, and fasting plasma glucose.