NUCB2 and diabetic kidney disease: We found that serum Nesfatin-1 level at a cut-off value < 8.09 mmol/L could be a marker for the detection of DM with 95% sensitivity and 74.3% specificity, serum Nesfatin-1 level at a cut-off value < 5.87 (mmol/L) could be a marker for detection of microvascular complications with 76.7% sensitivity and 67.3% specificity, and serum Nesfatin-1 level at cut off value < 5.46 (mmol/L) could be a marker for detection of DKD with 94% sensitivity and 60% specificity.