We observed that the increased PINK1 response in PD appeared predominantly driven by differences in males (Fig. 2a,b) with a 5.1-fold increase of PD vs. HC in males (Mann-Whitney p=0.09, Fisher’s exact p=0.02) compared to a 1.2-fold difference in female PD vs HC (Mann-Whitney p=0.23, Fisher’s exact p=0.63). The gene discussed is PINK1; the disease is Parkinson disease.