We compared the sum of reactivity to PINK1 and parkin in individual male PD vs. HC participants to reactivity in females, and we found a similar trend for an increased response towards these mitochondrial-associated proteins in males with PD (Fig. 2c, Mann-Whitney p=0.07), but not in females with PD (Fig. 2c, Mann-Whitney p=0.11). Here, PRKN is linked to Parkinson disease.