It was reported that the MET proto-oncogene, receptor tyrosine kinase (MET), regulates the expression level of hypoxia-inducible factor 1 alpha (HIF-1α) through a protein translation mechanism regulated by phosphorylation of EIF4G1 on serine 1,232 and showed that it has an impact on the disease-free survival of patients with NSCLC (Glück et al., 2018). Here, EIF4G1 is linked to non-small cell lung carcinoma.