To verify whether increased secretion of CXCL8 in lung cancer cells is caused by increased expression of the receptor for TNFSF10, TNFRSF10A, after knockdown of EIF4G1, the protein concentration of CXCL8 was detected in response to different concentrations of TNFSF10 in H1299vector and H1299shEIF4G1 cells, respectively. The gene discussed is TNFSF10; the disease is lung cancer.