In multivariate Cox regression analysis, we also found that PTBP3 expression was an independent prognostic marker for both overall survival (HR 0.549, 95%CI, 0.401–0.751; p < 0.001) and disease-free survival (HR 0.524, 95%CI, 0.375–0.732; p < 0.001) in patients with RCC (Table S2). This evidence concerns the gene PTBP3 and renal cell carcinoma.