PLOD1 and cyst: We analyzed the difference between the clinical indicators of the cyst group and the non-cyst group in girls with CPP and found that the estradiol level, LH peak, LH peak/FSH peak, uterine body and cervix length, and pituitary height in the cyst group were significantly higher than those in the non-cyst group, suggesting that pineal cysts may be related to the pubertal development process.