LINC00475 and central nervous system cancer: Additionally, isocitrate dehydrogenase 1 (IDH1) wild-type gliomas demonstrated a pronounced LINC00475 overexpression relative to IDH1 mutant gliomas (Fig. S1E), whereas, specifically in World Health Organization (WHO) grade III gliomas, patients without 1p/19q co-deletion exhibited markedly higher levels of LINC00475 relative to those with deletion status (Fig. S1F).