CD4 and tuberculosis: The candidate vaccine of ID93/GLASE TB has been examined for the MTB clinical-strain K (MTB-K) from the family of Beijing (the most common strain of MTB in South Korea) that showed the ability of ID93/GLASE to stimulate constant Th1-biased immune pathway of antigen-specific multifunctional CD4+ T-cell co-generating TNF-α, IFN-γ and IL-2, especially IFN-γ, which exhibited a significant response up to 10 weeks after exposure [45].