These results confirm, once again, that TRPV1 plays an important role in the pathophysiology of epilepsy, as observed previously (Jia et al., 2015; Saffarzadeh et al., 2015; Kong et al., 2019; Wang et al., 2019; Lazarini-Lopes et al., 2022). The gene discussed is TRPV1; the disease is epilepsy.