TRPV1 and major depressive disorder: Out of 13 transcripts of interest (CNR1, CNR2, GPR55, GPR110, TRPV1, MGLL, DAGLA, PLCB1, NAPEPLD, FAAH, ABHD6, PLA2G4A and ALOX8, Supplementary Table S2), none were considered significantly up- or down-regulated in MDD (Figure 1A), respectively defined as log2(fold change) >1 or < −1 and -log10(p) ≥ 1.3 (p = 0.05).