FOXP3 and type 1 diabetes mellitus: The importance of these cells in the prevention of autoimmune and inflammatory pathologies is best illustrated by the observation that individuals and mice with mutations in the gene encoding FOXP3/Foxp3, the “master” regulator for Treg function, develop lethal autoimmune and inflammatory pathology, of which type I diabetes (“T1D”) is, in humans, a prominent component (1).