Approximately half of MoMacs from TNFα-neutralized CGD mice adopted a phenotype that more closely resembled WT MoMacs (Figures 5C, D) showing downregulation of CD54 and Ly6C, along with upregulation of CD36 and CD206, although not to quite the extent of WT MoMacs, and upregulation of CD64 above that seen in the WT MoMacs (Supplementary Figure 10). This evidence concerns the gene FCGR1A and chronic granulomatous disease.