(31), in a prospective epidemiologic study of European patients with myocardial infarction, observed that Welsh Depression Scale scores were associated with elevated levels of IL-6 (OR 1.39), CRP (OR 1.30), intercellular adhesion molecule 1 (OR 1.22), and plasma fibrinogen (OR 1.36) after correcting for other risk factors compared to age-matched controls with angina pectoris or nonfatal myocardial infarction. The gene discussed is CRP; the disease is major depressive disorder.