Another study revealed that psoriasis patients displayed higher MBL levels than control subjects and that the level of MBL correlated positively with PASI score and psoriasis severity, and found that MBL assisted the differentiating and infiltrating processes of plasmacytoid dendritic cells in initial skin lesions of psoriasis, leading to the aggravation of disease severity (59). This evidence concerns the gene MBL2 and psoriasis.