TNRC6B deficiency syndrome, also known as global developmental delay with speech and behavioral abnormalities (GDSBA, MIM 619243), is caused by heterozygous variant in the TNRC6B (NM_001162501.2, MIM 610740) gene, located at 22q13.1, which contains 23 exons and encodes the trinucleotide repeat‐containing adaptor 6B protein involved in translational inhibition (Baillat & Shiekhattar, 2009; Granadillo et al., 2020). Here, TNRC6B is linked to Global developmental delay.