Although advances in medical and percutaneous therapies such as percutaneous coronary intervention (PCI), angiography, echocardiography, and low high‐density lipoprotein (HDL) cholesterol,13 copeptin,14 and B‐type natriuretic peptide15 factors have been used to predict HF,16, 17 HF patients are vulnerable to hospital readmission, high mortality, critical damage to the quality of life, and results in significant financial stress on the public health‐care system.17, 18. The gene discussed is AVP; the disease is hydrops fetalis.