Age, hyperlipemia, HYHA classification, clinical symptoms, CRP, LAC, neutrophil, lymphocyte, monocyte, eosinophil, basophil, BUN, eGFR, sodium, calcium, MB, NT‐proBNP, MR, TR, LVEF, transmitral peak E, TRPG, LAVI, E/e', TAPSE, RVFAC, IVC respiratory change, and beta‐blocker were potential confounders for 1‐year CVD‐cause mortality in patients with HFmrEF (Supporting Information S5: Table 2). The gene discussed is NPPB; the disease is familial hyperlipidemia.