The National Comprehensive Cancer Network guideline suggests the use of 5-fluorouracil plus oxaliplatin plus irinotecan combination therapy (FOLFIRINOX) or gemcitabine plus nanoparticle albumin-binding paclitaxel (nabPTX) combination therapy (GEM/nabPTX) as first-line chemotherapy in patients with advanced pancreatic cancer [3]. This evidence concerns the gene ALB and familial pancreatic carcinoma.