Compared with T2DM rats, the percentage of pancreatic Bax (Fig. 10C) and Caspase-3 (Fig. 10D) positive area was decreased (P < 0.05) (Fig. 10F) and the percentage of Bcl-2 (Fig. 10E) positive area was increased (P < 0.01) in control rats (Fig. 10F). The gene discussed is CASP3; the disease is type 2 diabetes mellitus.