CLU and endometriosis: In the study by Lucas ES et al.76, high expression of DIO2 was identified as a key marker in the divergence into decidual cells along with a cluster of cells expressing high CLU, ALDH1A1, ADAMTS5, ABI3BP, and CEMPI. Our analysis showed that the decidualizing cells from patients with endometriosis displayed decreasing expression of DIO2, CLU and ALDH1A1, but elevated expression of ADAMTS5, ABI3BP, CEMPI and COL14A1 (Supplementary Fig. 1D).