SMAD4 and endometriosis: We first performed a time-course transcriptomic analysis of the datasets to identify the genes that are expressed within each group as they undergo in vitro decidualization and identified that stromal cells from patients with endometriosis displayed gene expression signatures that were controlled by NFE2L2, a marker of oxidative stress, and SMAD4, the effector of TGFβ and BMP signaling.