ITGB1 and neoplasm: In addition, a series of studies found that the integrin ITGB1, consisting of the β1 subunit, participates in promoting the progression of hepatocellular carcinoma, breast cancer, and pancreatic cancer, maintaining tumor cell viability and resistance to irradiation through the interplay of transduction of various intracellular communication pathways as key adhesion molecules [4, 7].