The expression profile and prognostic significance of ITGB1 in a variety of cancers were investigated, and the findings demonstrated that ITGB1 can be used as a risk factor or prognostic factor for a number of malignancies, further emphasizing the possibility of ITGB1 as a prognostic biomarker for cancer and establishing a foundation for a thorough comprehension of ITGB1's function in tumor immunotherapy. Here, ITGB1 is linked to cancer.